Abstract:[Objective] To introduce the design and application of the inverted L-shaped approach for proximal humerus fractures andthe preliminary clinical results. [Method] From June 2021 to June 2022, 20 patients with proximal humeral fractures were treated throughan inverted "L" approach. A horizontal skin incisions were extended along the acromial process from the anterolateral to the posterolateralborder. After skin, subcutaneous and fascial layers were cut, and the incision was extended about 4 cm in length down to the lateral arm.The deltoid was detached from the acromial process along the length of the horizontal incision, the deltoid flap was stretched backwards, theexposed area was identified. As the bone fragments and blood clots were removed, the fracture was reduced, were temporarily immobilizedwith 2 Kirschner wires, and then fixed by PHILOS plate. [Results] The exposed areas measured in the cadaveric specimens were ranked asinverted "L" approach, deltoid split approach and pectodeltoid approach [(20.6±5.6) cm2 vs (15.1±3.7) cm2 vs (14.0±5.0) cm2, P<0.001]. Allpatients had open reduction and internal fixation performed successfully without any complications, such as nerve damage during the opera-tion. All patients were followed up for an average of (13.2±3.4) months. The X-rays showed that all fractures were healed 6 months after theoperation, with healing time of (127.5±11.5) days on average. The Constant score increased significantly from (45.3±2.6) before surgery to(94.9±2.2) at the last follow-up. [Conclusion] This inverted L approach is convenient and feasible for the treatment of proximal humerusfracture with satisfactory early results.