Abstract:[Objective] To measure the safe height and angle of anteroposterior screw placement in distal articular dome of the tibia.[Methods] The vertical distance of distal articular surface dome to the connecting line of the lowest point of the anterior and posterior tibiallips, and the angle between the tangent line of the anterior and posterior lips of the distal tibia were measured on the T2 weighted MRI imag-ines in 100 patients, including 64 males and 36 females. The differences between male and female groups and left and right groups werecompared and analyzed. [Results] The male had significantly greater vertical distance of distal articular surface dome to the connecting lineof the lowest point of the anterior and posterior tibial lips on the right side than the female, with statistically significant difference [(5.6±0.9)mm vs (5.1±0.8) mm, P=0.035]. The male had less angle between the tangent line of the anterior and posterior lips of the distal tibia on theleft and right sides than the female, but the difference was not statistically significant (P>0.05). In both male and female, the vertical dis-tance of distal articular surface dome to the connecting line of the lowest point of the anterior and posterior tibial lips on the left side wasgreater than that on the right side, despite of the fact that difference was not statistically significant (P>0.05). Both male [(37.6±5.0)° vs(32.2±8.2)°, P=0.003] and female [(37.8±4.6)° vs (32.7±7.3)°, P=0.026] had significantly greater angle between the tangent line of the ante-rior and posterior lips of the distal tibia on the left side and the right side. [Conclusion] As anteroposterior screw placement on the distaltibia, the lower edge of the screw should be at least 7 mm above the edge of the anterior lip of the tibia, which in male should be higher thanthat in the female on the right side. If further longer screws are implanted, tilting the screw at least 42° to the proximal tibia, with the leftside more tilting than the right side in both men and women.