Abstract:[Objective] To evaluate the clinical consequence of Tightrope combined with lateral plate fixation for Lisfranc injury.[Methods] A retrospective analysis was performed on 30 patients who had Lisfranc injury treated by the above methods from January 2020to October 2023. Clinical and imaging data were evaluated. [Results] All the patients were successfully operated on without any seriouscomplications such as vascular and nerve injury, while with the average operation time of (40.2±10.7) min, and average blood loss of (30.3±5.0) mL. All the patients were followed up for an average of (12.8±2.0) months. With time preoperatively, 3 months after surgery and the lastfollow-up, the VAS score [(5.6±1.2), (3.0±0.8), (1.9±1.1), P＜0.001], AOFAS score [(39.8±3.6), (60.3±6.0), (86.0±4.3), P＜0.001] were sig-nificantly improved. As for imaging, lateral shifting of the second metatarsal base [Y/N (30/0), (0/30), (0/30), P＜0.001], dorsal steps [Y/N,(18/12), (0/30), (0/30), P＜0.001] were significantly corrected over the time period abovementioned. However, the distance between the bas-es of the first and second metatarsals [(5.7±1.3) mm, (1.9±0.3) mm, (1.6±0.2) mm, P＜0.001] was significantly reduced. [Conclusion] Thetight rope combined with lateral plate fixation does achieve satisfactory clinical consequence in the short term for Lisfranc injury, and is asafe and reliable surgical technique.