Abstract:[Objective] To verify the impact of accessory navicular bone of foot (AN) on posterior tibialis tendon dysfunction (PTTD) byquantitative measurement of posterior tibialis tendon (PTT) thickness with MRI. [Methods] From January 2019 to August 2022, 116 pa-tients who received MRI examination of PTT in our hospital were included in this study. The patients with medial foot pain and MRI presen-tation of PTT injury or effusion around the tendon insertion were defined as the abnormal group, while those with no symptoms and normalMRI were defined as normal group. In addition, the two groups were further defined into 4 subgroups according to different AN types, in-cluding non AN group, type I AN group, type II AN group and type III AN group. The measurement results of the two groups were com-pared, and ROC analysis was performed according to whether abnormality and PTT thickness. [Results] There was no significant change inPTT thickness of all subgroups in normal group (P>0.05). PTT thickness of type II AN subgroup in abnormal group was significantly in-creased (P<0.05). Compared with the normal group, the type II AN subgroup in abnormal group had significantly greater PTT thickness of[(4.1±1.2) mm vs (5.5±0.6) mm, P<0.001], despite of the fact that no significant difference in PTT thickness between the two groups in othersubgroups was noted (P>0.05). As results of ROC analysis PTT thickness of type II AN subgroup predicting whether abnormality, the bestcut-off point was of 4.7 mm, sensitivity of 87.5%, specificity of 85.7%, with area under curve (AUC) of 0.875. [Conclusion] In PTTD, thepresence of type II AN can increase the thickness of PTT and aggravate the lesion.