胶原蛋白软骨支架修复膝关节软骨损伤

Collagen protein cartilage scaffold for repairing knee cartilage injury

摘要:

[目的]介绍胶原蛋白软骨支架修复膝关节软骨损伤的的手术技术和初步临床结果。[方法]2 例膝关节软骨损伤患者接受上述手术治疗。取膝关节常规前内侧、前外侧入路，探查清理周围增生的滑膜组织，在关节镜下于软骨 IV 度损伤区域行微骨折术，后用气辅机烘干关节腔内液体，使关节腔干燥，将准备好的胶原蛋白软骨支架注射填充至软骨损伤区域。 [结果] 术后 3 个月复查，2 例患者均恢复正常活动，屈曲最大角度均可达 130°，Lysholm 评分 83~85 分，IKDC 2000 评分 79~83 分，疼痛 VAS 评分 0 分。[结论]2 例患者软骨损伤区域得到修复，患肢功能活动改善，疼痛症状缓解，效果满意。

Abstract:

[Objective] To introduce the surgical technique and preliminary clinical results of collagen protein cartilage scaffold for repairing knee cartilage injuries. [Methods] Two patients underwent abovesaid surgical operation. As routine anteromedial and anterolateral portals were created, arthroscopic examination was conducted with debridement of hyperplastic synovial around the lesion, and microfracture was performed in the grade IV cartilage defect area under arthroscopy. After drying the joint cavity by suctioning intra-articular fluid, the prepared collagen protein cartilage scaffold was injected and filled into the cartilage defect area. [Results] Both patients recovered normal activities 3 months postoperatively, with maximum flexion of 130°, Lysholm scores of 83~85, the IKDC 2000 scores of 79~83 and pain VAS score of 0. [Conclusion] The cartilage defect in the two patients are repaired effectively, with improved limb function and symptom relief, achieve satisfactory preliminary outcomes.