Abstract:[Objective] To investigate the clinical efficacy of double-incision double-plate internal fixation (DIDPIF) in the treatment of Schatzker type VI tibial plateau fracture (TPF). [Methods] A retrospective study was conducted on 54 patients who received DIDPIF for Schatzker type VI TPF in our hospital from June 2021 to June 2023. The clinical and imaging data were evaluated. [Results] All the 54 patients were successfully operated on, with an average operation time of (100.0±11.6) min, an average intraoperative blood loss of (270.5± 40.3) mL, an average walking time of (9.4±2.5) days, and an average hospital stay of (10.2±2.0) days. No complications, such as neurovascular injury and incision infection occurred in anyone during perioperative period. They were followed up for a mean of (15.0±2.0) months. The VAS score significantly decreased at the last follow-up compared with that 3 months after surgery [(1.0±0.3) vs (2.3±0.6), P<0.001], whereas the HSS score [(90.0±8.5) vs (63.2±7.4), P<0.001] and knee extension-flexion ROM [(119.4±4.6)° vs (90.3±3.7)°, P<0.001] significantly increased. Compared with those immediately after surgery, the MPTA and PTS remained unchanged remarkably at the latest follow-up (P> 0.05), and there was no a significant variation in K-L scale between the time points 3 months after surgery and latest follow-up (P>0.05). [Conclusion] DIDPIF for Schatzker type VI TPF has advantages of good anatomic reduction quality and strong stability, which is conducive to the improvement of knee function and motion.