Abstract:[Objective] To investigate preliminary results of direct anterior approach (DAA) hip arthroplasty in Xizang area. [Methods] A retrospective study was done on 23 patients who received DAA hip arthroplasty from August 2023 to August 2024. The Clinical and imaging data were evaluated. [Results] The 23 patients were operated on successfully without serious complications, with the average operation time of (109.4±32.5) min, the average incision length of (12.9±1.5) cm, the average intraoperative blood loss of (317.4±148.9) mL. All the patients were followed up for a mean of (13.5±1.2) months. With time preoperatively, 3 months postoperatively and the latest follow-up, the VAS score was significantly decreased [(9.1±0.6), (3.4±0.8), (2.1±0.5), P<0.001], while the hip flexion-extension range of motion (ROM) [(58.2±29.7)°, (117.0±8.6)°, (127.0±5.2)°, P<0.001] and Harris score [(31.5±18.2), (96.4±1.4), (96.7±2.1), P=0.010] were significantly increased. As for imaging, there were no significant changes in the leg length discrepancy, femoral neck-shaft angle, acetabular abduction angle and acetabular anteversion after surgery compared with those before surgery (P>0.05). [Conclusion] In Xizang, the DAA hip arthroplasty does achieve good initial clinical consequence, with advantages of less risk of dislocation, faster recovery, higher satisfaction, and better hip function recovery.