Ilizarov技术治疗感染性骨不连的研究进展

Research progress of Ilizarov technique in the treatment of infectious nonunion

摘要:

感染性骨不连是骨折后出现的严重并发症，治疗困难且极大可能会导致患者截肢和永久性残疾。传统治疗方法如抗生素应用、病灶清除等仅是对症处理，不能根治，且存在感染复发等缺陷。众多研究发现，Ilizarov 技术能够通过截骨彻底清除感染病灶以根治感染，并利用轴向牵张应力等刺激细胞增殖和血管形成，进而促进骨形成，最终治愈感染性骨不连，且多项研究已证实其疗效确切。本文对国内外采用 Ilizarov 技术治疗感染性骨不连的研究进行综述，并结合当前医疗技术发展对其进行前景展望，以期为今后的临床治疗提供借鉴。

Abstract:

Infectious nonunion is a serious complication of the fracture that is difficult to treat and can lead to amputation and permanent disability. Traditional treatments, including antibiotic application and lesion debridement, are symptomatic methods with disadvantages such as recurrence of infection. Many doctors have found that the Ilizarov technique can completely remove the infectious lesion through osteotomy, cure the infection, and apply axial distraction and squeezing stress to stimulate cell proliferation and angiogenesis, promote bone formation, and ultimately cure infectious nonunion, and its efficacy has been confirmed by several studies. This article briefly reviews the research on the use of Ilizarov technology in the treatment of infectious non-union at home and abroad, looks forward to its prospect based on the current development of medical technology to provide reference for future clinical treatment.