Abstract:[Objective] To introduce the surgical technique and preliminary clinical outcome of unilateral biportal endoscopic discectomy for thoracic ossified intervertebral disc protrusion through the paravertebral approach. [Method] As portals for unilateral biportal endoscopy was established with continuous normal saline irrigation, the T12 facet tip was identified under the endoscope and the corresponding intervertebral foramen area was burred and expanded to expose the ossified lesion gradually from the intervertebral foramen to the spinal canal. With the up-low boundary of the lower edge of the T11 pedicle and the upper edge of the T12 pedicle, and the in-out boundary of the midpoint of the intervertebral foramen to the left and right ligamentum flavum, the protruded and ossified nucleus pulposus was removed by a burr with protective sheath inferolateral to the dura mater. After proper compression achieved, a drainage tube was placed and the incisions were sutured and bandaged. [Results] During the operation, the ossified intervertebral disc compressing the spinal cord and the hyperplastic ligamentum flavum were successfully removed. On the second day after the operation, the drainage volume was of 20 mL and the drainage tube was removed. The postoperative lumbar CT and MRI showed that the protruded and ossified nucleus pulposus tissue in the T11~T12 segment had been properly removed, and the compression of the nerve root and the dural sac was significantly relieved. Three days after the operation, the patient reported significant improvement in bilateral lower limb pain and weakness, with VAS score of 4 and remarkably improved neurological motor function. [Conclusion] The unilateral biportal endoscopic technique through the paravertebral approach greatly overcomes the operational blind area caused by the narrow thoracic spine anatomy, avoids the complex nerve root distribution in the spinal canal, reduces the risk of traction on the spinal cord, and achieves comprehensive spinal decompression.